Opioid Treatment Programs (OTPs)

COVID-19 Information from the Office of Behavioral Health

Please visit the Office of Behavioral Health's COVID-19 Information Page for the latest guidance and resources.

Please visit the Office of Behavioral Health's COVID-19 Guidance for OTPs for the latest guidance and resources from SAMHSA and OBH.


This educational web page was developed to provide support to providers and individuals seeking to gather information related to the use of medications to treat Opioid Use Disorder (OUD).  Persons with OUD are dependent upon opioids (e.g. prescription pain pills oxycodone and hydrocodone), or the illicit opiate heroin) and receive medication assisted treatment (MAT) through Opioid Treatment Programs (OTP’s).

In the United States, the treatment of opioid dependence with medications is governed by the Certification of Opioid Treatment Programs, 42 Code of Federal Regulations (CFR) 8. This regulation created a system to accredit and certify opioid treatment programs (OTPs).

OTPs provide medication-assisted treatment (MAT) for people diagnosed with an opioid-use disorder. MAT patients also must receive counseling, which can include different forms of behavioral therapy. Learn more about medication and counseling treatment for substance use disorders

The Office of Behavioral Health under the Colorado Department of Human Services further adds to the oversight of OTP’s in the Code of Colorado Regulations 2 CCR 502-1.