The Colorado Department of Public Health and Environment (CDPHE) Institutional Review Board (IRB) responsible for protecting the rights and welfare of human research subjects recruited to participate in research activities conducted under the auspices of the Department.
The federal regulation Protection of Human Subjects, 45 CFR 46, also known as the Common Rule, governs the actions of the CDPHE IRB. The IRB's authority is granted by the U.S. Department of Health and Human Services based on a CDPHE commitment to comply with the provisions of 45 CFR 46. All research studies involving human subjects must be reviewed by the IRB regardless of the funding source. The IRB has the authority to approve, require modifications in, or disapprove all research activities that fall within its purview.
This process is designed to ensure that research protocols protect the rights and welfare of human subjects - for example, by minimizing risks, selecting subjects equitably, obtaining informed consent and ensuring privacy and confidentiality. IRB approval must precede initiation of any work involving human subjects.
The membership of the IRB is diverse while maintaining the level of expertise required to properly review human subjects research protocols. Currently there are nine members of the IRB, of whom five are CDPHE employees and three are from outside the Department. A CDPHE-affiliated member serves as the Boards chair.
The information CDPHE researchers need to successfully address human subjects research protections can be found on this Web page and by contacting the CDPHE IRB Administrator .