Rates* and Case Fatality Percents of Invasive Haemophilus influenzae by Age Group:
Denver Metropolitan Area^ and Colorado, 2010

AGE GROUP (years) Cases Deaths
EIP^ No. (EIP Rate*) State No. (State rate*) State No. (% of cases)
<=1 5 (7.3) 11 (8.2) 1 (9.1)
2-4 . . 1 (0.5) 0  
5-14 4 (1.2) 9 (1.3) 0  
15-24 2 (0.6) 7 (1.0) 0  
25-34 . . 3 (0.4) 0  
35-49 5 (0.9) 9 (0.8) 0  
50-64 6 (1.3) 13 (1.3) 1 (7.7)
65+ 22 (8.9) 33 (5.9) 5 (15.2)
Total 44 (1.8) 86 (1.7) 7 (8.1)

*Rates are per 100,000 population and based upon 2011-based population estimates, State Demography Office - DOLA
^EIP area: Adams, Arapahoe, Denver, Douglas, and Jefferson counties.

 


Rates* of Invasive Haemophilus influenzae by County:
Denver Metropolitan Area^, 2010

COUNTY OF RESIDENCE Cases
No. (Rate*)
ADAMS 8 (1.8)
ARAPAHOE 7 (1.2)
DENVER 12 (2.0)
DOUGLAS 3 (1.1)
JEFFERSON 14 (2.6)

*Rates are per 100,000 population and based upon 2011-based population estimates, State Demography Office - DOLA
^EIP area: Adams, Arapahoe, Denver, Douglas, and Jefferson counties

 


Sterile Sites from which Haemophilus influenzae was Isolated:
Denver Metropolitan Area^, 2010

SITE OF ISOLATION No.* (% of cases)
Blood 42 (95.5)
Pleural fluid 2 (4.5)
CSF 1 (2.3)
Joint fluid 1 (2.3)

*H.flu was isolated from one site in 42 cases and multiple sites in 2 cases (Total cases=44)
H.flu was isolated only from blood in 40 cases (90.9%)
^Emerging Infections Program area: Adams, Arapahoe, Denver, Douglas, and Jefferson counties

 


Clinical Syndromes Associated with Invasive Haemophilus influenzae Disease:
Denver Metropolitan Area^, 2010

CLINICAL SYNDROME No.* (% of cases)
Bacteremic pneumonia 26 (59.1)
Bacteremia only 9 (20.5)
Meningitis 3 (6.8)
Epiglottitis 2 (4.5)
Otitis media 1 (2.3)
Cellulitis 1 (2.3)
Septic arthritis 1 (2.3)

*Some cases may have more than one syndrome (Total cases=44)
^Emerging Infections Program area: Adams, Arapahoe, Denver, Douglas, and Jefferson counties

 


Underlying Conditions Associated with Invasive Haemophilus influenzae :
Denver Metropolitan Area^, 2010

UNDERLYING CONDITION No.* (% of cases)
Diabetes 10 (22.7)
Current Smoker 7 (15.9)
Emphysema/COPD 7 (15.9)
Atherosclerotic Cardiovascular Disease 6 (13.6)
Alcohol Abuse 4 (9.1)
Heart Failure/CHF 3 (6.8)
Immunosuppressive Therapy 2 (4.5)
Leukemia 1 (2.3)
Hodgkin"s Disease 1 (2.3)
Asthma 1 (2.3)
Renal Failure/Dialysis 1 (2.3)
Cerebral Vascular Accident/Stroke 1 (2.3)

*13 cases had more than one underlying condition
8 (18.2%) had no underlying conditions; 0 cases were unknown (Total cases=44)
^Emerging Infections Program area: Adams, Arapahoe, Denver, Douglas, and Jefferson counties

 


Invasive Haemophilus influenzae Serotypes:
Denver Metropolitan Area^, 2010

Serotype No.* (% of isolates)
Not Typeable 32 (72.7)
f 7 (15.9)
a 2 (4.5)
e 2 (4.5)
b 1 (2.2)
Total 44 (100.0)

*Based upon testing of 44 isolates (Total cases=44)
Testing performed by the CDPHE Laboratory
^Emerging Infections Program area: Adams, Arapahoe, Denver, Douglas, and Jefferson counties